FMC Content

The Future of Male Contraception

A successful conference was held in Seattle, Washington at the Edgewater Hotel

September 27th & 28th, 2007

 

The link to the program for the 2007 FMC meeting. This includes a list of the speakers and the

individuals that submitted and presented posters for the Thursday night event.

 

Please note the list of attendees that registered for the conference:
Registration List

The speakers' abstracts have been consolidated into one Word document for your convenience
abstracts

The poster presentation abstracts have been consolidated into one Word document for your convenience
poster abstracts

 

Please reveiw each speakers' abstract:
Oral Testosterone Enanthate plus Dutasteride - John Amory
Intra Vas Device - Janelle Antil
Orally Active Androgens - Barbara Attardi
Inhibitors of catecholamine and adenosine analog action - Donner Babcock
Na,K-ATPase - A sperm-specific isoform as a target for male contraception - Gustavo Blanco
Challenges of the Blood Testes Barrier - Robert Braun
Nestorone and Testosterone Gels - Christina Wang
Drug Targeting to the Testis - C. Yan Cheng
CatSper; The Sperm-Specific Calcium Channel as a Target for Male Contraception- David Clapham
Soluble Adenylyl Cyclases - Marco Conti
K+ Channel Blockers and Sperm volume regulation: a contraceptive opportunity? - Trevor Cooper
Nonsteroidal SARM Ligands - James Dalton
High-throughput Screening & Drug Design - Gunda Georg
CDB-4022: a Potential Oral Nonsteroidal Male Contraceptive - Sheri Hild
Etonogestrel implants and TU - Wendy Kersemaekers
Oral Acyline - Thomas Leonard
Recovery after Male Hormonal Contraception - Peter Liu
ZPBPs in Sperm-Egg Interactions and Acrosome Formation - Martin Matzuk
PKA as a Target for Male Contraception - Daniel Morgan
Progestin Effects on Gonadotropin Levels - Eberhard Nieschlag
Normal and Subnormal Semen Parameters - Eberhard Nieschlag
Novel Sperm Glycolytic Enzymes as Contraceptive Targets - Deborah O'Brien
Eppin: Development as a Male Contraceptive Target - Michael O'Rand
DMPA + T Gel /Acyline - Stephanie Page
Acceptability of Male Contraceptives - Albert Radlmaier
Testicular Gene Expression after Hormones and Heat - Ronald Swerdloff
A model for the anti-spermatogenic action of Gamendazole - Joseph Tash
Na+H+ Exchanger regulation of sperm motility - Dan Wang
Retinoic Acid Alpha Receptor Inhibitor as a Contraceptive - Debra Wolgemuth


Abstracts for poster session
1. The Na,K-ATPase a4 Isoform - Gustavo Blanco
2. Neutersol® from Laboratory to Market-Lessons Learned - Brenda Campbell
3. Design, Synthesis and Biological Evaluation Antispermatogenic Agents - Ramappa Chakrasali
4. Aquapores in Sperm Volume Regulation - TG Cooper
5. Live Imaging to Visualize the Effect of the Candidate Male Contraceptive Agent - Jeffrey L. Cotitta
6. Selective Inhibition of Glyceraldehyde 3-Phosphate Dehydrogenase S - Polina V. Danshina
7. Synthesis and Biological Evaluation of Flavopiridol Analogs as Male Contraceptive Agents - Keith C. Ellis
8. Discovery of Novel cdk2 Inhibitors - Rawle Francis and Andreas Becker
9. sAC Assay Implementation and Validation - Rawle Francis and Bernhard Trinczek
10. Identification and characterization of genes related to meiosis in the postnatal ltestes - Michael Griswold
11. Synthesis and Evaluation of Imino Sugars as Male Contraceptive Agents - Xinxiang Gu
12. In-Vitro Ceramide-Specific Glucosyltransferase Assay - Vijayalaxmi Gupta
13. Administration of male contraceptive C57BL/6 in mice differences in anti-spermiogenic efficacy - Vijayalaxmi Gupta
14. SpermCheck® Immunochromatographic Vasectomy. - John C. Herr
15. Targeted Deletion of TSSK 1 & 2 Causes Male Infertility During Flagellogenesis - John C. Herr
16. The sperm annulus is a septin-ringed organelle critical for producing fertilization-competent sperm - Gary R. Hunnicutt
17. Immunoproteomics approach for identification of domain specific epididymal proteins - Vrinda Khole
18. Analysis of FNDC3A, a novel protein required for spermatid - Sertoli adhesion in mice - Grant MacGregor
19. SUMOs and SUMOylation as Promising Targets for Male Contraceptive Development in Humans - Patricia L. Morris
20. CatSper and KSper, the two pH-sensitive sperm flagellar currents - Betsy Navarro
21. Evaluation of four-membered analogs of DNJ as potential male contraceptive agents - Subhashree Rangarajan
22. Confirmation of interleukin 1-alpha (IL-1a) as an early response gene - Kendall S. Smith
23. Development and testing of novel sAC inhibitors as potential male contraceptive agents - Joseph S. Tash
24. Increased public support for male contraception research: survey data - Kirsten M. Thompson
25. Roles of glycosylated sphingolipids in male germ cell development - Aarnoud C. VanderSpoel
26. Characterization of components of highly conserved machinery for germ cell development - Eugene Y. Xu


Programs Offering Assistance for Academic Drug Development WEBSITES:

NIH-RAID Pilot Program - http://nihroadmap.nih.gov/raid/

Type 1 Diabetes RAID (T1D) - www.niddk.nih.gov/fund/diabetesspecialfunds/T1D-RAID

NIAID - www3.niaid.nih.gov/research/resources/

NINDS - accessible.ninds.nih.gov/funding/research/translational

NIDA - grants.nih.gov/grants/guide/pa-files/PAS-06-066.html

NCI - dtp.nci.nih.gov/docs/raid/raid_index.html

 

 

Meeting sponsored by:
National Institute of Child Health and Human Development,
National Institutes of Health, DHHS
University of Washington, Seattle, Washington
CONRAD
World Health Organization